Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

M.Raubo

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis: Edema uremic encephalopathy. Autopsy examination of 57-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with H-E, Cresyl violet, Heidenhain and Van Gieson's method.At all intersections in the white matter of the brain, cerebellum, and medulla, small poorly defined foci of myelin translucencies were found. At high magnification, swelling and disintegration of myelin fibers and swelling of glial cell protoplasm were visible in these fields. Sometimes the foci were concentrated around small vessels, sometimes they were located completely independent from the vessels. Around larger vessels areas of typical spongiform necrosis and extensive areas of incomplete and not sharply demarcated demyelination were observed. The gray matter was not affected originally. Numerous translucencies and neuronal degeneration corresponded to altered cortical capillaries. The whole picture most closely resembled edematous uremic encephalopathy. A clinical syndrome of psychiatric disorders could also support this diagnosis. In urine obtained post-mortem from the kidney, pathological changes were found.Histological diagnosis: Encephalopathia oedematosa vere similiter uraemicae.

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:193306

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open