Title:

File of histopathological evaluation of nervous system diseases (1966) - nr 117/66

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

A, Taraszewska, lek.

Date issued/created:

1966

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Vascular disaeses - encephalomacia

Abstract:

Histological diagnosis: Encephalomalacia incipiens in reg. nucleorum basalium dext.Focus malaciae parvus cortieis cerebelli. Autopsy examination of 72-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, PAS and van Gieson method.A specimen from the right basal ganglia revealed a focus of fresh necrosis without tissue disintegration, involving the insular cortex, external and extrema capsule, claustrum, striatum white matter semioval center and partly internal capsule, without clear demarcation borders. Throughout the area a large loss of cellular elements, both neurocytes in the striatum, cortex, and glial cells were seen. The remaining cells were all severely damaged, regressive forms of gliosis, and ischemic changes were observed. The white matter showed atrophy of glial cells and stimulated vascular endothelium. In the gray matter, scattered single macrophages were seen in some areas. In the thalamus, atrophy of neurocytes and extensive damage to preserved cells due to accumulation of fatty substances were also observed. The vessel walls showed fibrous changes. In the cerebellum, necrosis was seen completely destroying the cortex of several cerebellar gyri.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open