RCIN and OZwRCIN projects

Object

Title: File of histopathological evaluation of nervous system diseases (1966)- nr 201/66

Date issued/created:

1966

Resource type:

Text

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

M.Dąmbska, dr hab.

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Maple Syrup Urine Disease (MSUD). Autopsy examination of 3-month-old baby was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained by Hematoxylin-eosin and Cresyl violet stain as well as Kluver-Barrera and Kanzler-Arendt methods. Additionally, frozen section was stained by Sudan III.Very weak coloring in staining for myelin was noticed in all sections of the white matter. Partial myelination was seen in the short tracts of the basal ganglia, in the axis of some convolutions of the cerebral hemispheres and in the cerebellar hemispheres. In poorly myelinated areas a tissue spongiosis was observed. Impaired myelination was accompanied by fibrous gliosis, more pronounced in structures with severe spongiosis and in their close vicinity. In Sudan III staining, small fat droplets around glial nuclei were seen in some areas, e.g. in the optic tract and partially in the cerebellar pathways, with a surprisingly small number of fat droplets around the vessels. In other non-myelinated areas Sudan III staining was negative

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:193504

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open

Edition name Date
opis nr 201/66 Feb 1, 2022
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