Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

L. Iwanowski, doc

Miejsce wydania:

Warsaw

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis: Encephalomalacia partim haemorrhagica hemisphaerii Dextri cerebri. Stus lacunaris. Oedema et hyperaemia cerebri. Artiosclerosis gradus majoris. Autopsy examination of 75-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with H-E, Heidenhain and Van Gieson's method.There was extensive diffuse necrosis involving both the cortex and white matter in the left occipital region. In the white matter scattered foci of hemorrhagic necrosis were seen. Cellular infiltrates consisting mostly of multinuclear leukocytes were found within the necrotic area. Macrophages also appeared in the perivascular infiltrates. At the border of necrosis there was visible malacia, and similar findings were observed in the insular cortex. Specimens of the left hemisphere contained areas of spongiosis of the frontal, parietal and amonal cortex. Loss of nerve cells was noticed, but layering was preserved. Extravasated blood was present in the subarachnoid space. Significant cellular and fibrous reaction of the soft meninges was observed. In the midbrain, spongiosis within the substancia nigra was evident. Features of edema and congestion were seen throughout the brain. The larger caliber arteries had moderately hypertrophied and fibrotic muscular layer. Smaller arteries and arterioles showed predominantly fibrotic changes without marked luminal narrowing. No vitreous changes were seen.

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:197126

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open