Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

L.Iwanowski, doc

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalopathia senilis status lacunaris et encephalomalaciae trunci. Autopsy examination of 86-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Cresyl violet, Orcein, Heidenhain, Holzer, Bielschowsky, Perdrau’s and Van Gieson's method.Atrophic changes were observed in the cerebral cortex, most severe in the frontal lobe. Areas of softening without neurofibrillary changes were seen. The above changes were accompanied by gliosis. On the other hand, in the stem, a focus of malacia was found on one side of the sternum and in the cerebellar folia. The parenchymal vessels were thin-walled, the basal vessels with slight atheromatous changes, without obvious narrowing of the vessel lumen. There was no macrophage infiltrate, only histiocytic reaction was observed in the meninges of the frontal lobe.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197015

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open