Title:

File of histopathological evaluation of nervous system diseases (1965) - nr 76/65

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

L. Iwanowski, dr

Place of publishing:

Warsaw

Date issued/created:

1965

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Vasular diseases - atherosclerosis

Abstract:

Histological diagnosis: Status lacunaris. Oedema et hyperaemia cerebri. Arterio et arteriosclerosis gradu maioris. Autopsy examination of 71-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Heidenhain and Van Gieson's method.In specimens from the basal nuclei, numerous small post-malacia cavities were observed, without macrophage reaction. The nerve cells were moderately thinned and quite rich in lipofuscin deposits. Also, moderate thinning was present in the cerebral cortex. In the frontal, central and parietal cortex, areas of tissue spongiform changes occupying the entire cortex or segmentally some layers were visible. There was loss of white matter cells adjacent to the cortex in the central area. Focal areas of spongiform changes were observed also in the midbrain and pons. Marked thinning with cell disintegration was present in the granular layer of the cerebellum. There were features of edema and congestion as well as diffuse gliosis throughout the brain, especially in the white matter and marginal layer of the cortex. The soft meninges were thickened with visible single macrophages. The larger caliber arteries had atherosclerotic plaques.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open