Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

M.Dąmbska, dr hab.

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalopatia post kernicterus. Autopsy examination of 3-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Holzer, cresyl-violet, Heidenhain, Kanzler-Arendt and Van Gieson's method.The basal ganglia clearly showed cell loss and damage in the globus pallidus. These were accompanied by fibrous gliosis. Cellular damage and vacuolation were also seen in the head of the caudate nucleus. Perivascular thinning of the tissue was also observed there. In the cerebral cortex, cells showed diffuse damage. In the cerebellum, the lesions mainly involved cells of the dentate nucleus. Myelin pattern in the cerebral hemispheres and brainstem was within the normal range.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197025

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open