Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

Zelman, I. dr med.

Miejsce wydania:

Warsaw

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis: Focus encephalomalaciae recens lobi frontalis, Stus lacunaris.Autopsy examination of 62-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain sections stained with Hematoxylin-eosin and van Gieson and brain frozen sections stained with Bielschowsky method.A focus of very early necrosis was found in the frontal area, in the cortex and white matter. The vessels within the focus were characterized by highly stimulated and swollen endothelium, and larger vessels showed prominent atherosclerotic changes. An irregular focus of malacia was seen at the border of the putamen and capsula externa. Some perivascular areas became extensive sinuses and only peripherally more or less abundant clusters of macrophages were observed, sometimes with admixture of histiocytes and single fibroblasts. In the vicinity of this focus, a distinct density of cellular glia was seen. The vessels had atheromatically altered walls /atheromatous, vitreous, fibrous-vitreous/ with symptomatic lymphocytic infiltrates. Accurate assessment of the extent of cellular damage and edema was impossible due to decay.

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:209441

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open