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File of histopathological evaluation of nervous system diseases (1963) - nr 100/63
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Place of publishing: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Encephalopathies and Myelopathies
Abstract:Histological diagnosis: Encephalopathia uraemica simplex.Autopsy examination of 20-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, van Gieson and Heidenhain method.The most advanced changes affected the cortex of all sampled areas. Focal perivascular and diffuse desolations leading to obliteration of layered pattern were found. The atrophied neurons were replaced by necrosis. Cortical capillaries were mediocrely filled, perivascular spaces were well defined. Venous stasis was observed in the white matter. Myelin preparations showed myelin sheath edema. In the basal ganglia, perivascular spaces were quite significantly widened; vessel walls were hypertrophied. Several small circular hemorrhages were found in the pons. Intravascular lympho- and leukocytic thrombi were seen in some vessels. The meninges were edematous.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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