Publisher:

Państwowy Zakład Wydawnictw Lekarskich

Place of publishing:

Warszawa

Type of object:

Journal/Article

Abstract:

Results of morphological and histochemical studies on the retina in cases of infantile and late infantile amaurotic idiocy are reported.The morhological pattern of the retina in the first case corresponds to alterations of the Tay-Sachs type. The second case represents the Batten type of lesion.On the basis of their histochemical properties, the intracellular deposits in the cytoplasm of the ganglion cells of the retina, in both cases, may be defined as acid glycolipid compounds containing neuraminic acid and combined with the structural cell protein. In both types of the disease these compounds are virtually identical.Comparison of the histochemical character of the deposits in the ganglion cells of the retina and in the cerebral nerve cells showed that they are identical in the late-infantile form, but exhibit significant differences in the infantile form. Apparently, the retinal glycolipids become „mature“ earlier than the cerebral glycolipids.

Relation:

Polish Medical Journal

Volume:

3

Issue:

1

Start page:

142

End page:

155

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:70576

Language:

eng

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open