Subtitle:

Effect of indomethacin on ischemic damage of sector CA1 of the horn of Ammon in Mongolian gerbils

Publisher:

Zakład im. Ossolińskich - Wydawnictwo Polskiej Akademii Nauk

Place of publishing:

Wrocław ; Warszawa ; Kraków

Type of object:

Industrial heritage site

Abstract:

The protective influence of indomethacin on selective damage of Ca1 neurons of Ammon’s horn resulting from short lasting cerebral ischemia was studied. Experiments were performed on Mongolian gerbils in which common carotid arteries were bilaterally ligated for 5 or 7.5 min. The animals were given intraperitoneal injection of indomethacin in a dosis of 8 mg/kg b.w. either 45 min prior to cerebral ischemia or 3 h after release of carotid ligation. Animals with doubled dosis of indomethacin given 45 min before and 5 h after ischemia formed an additional experimental group. Untreated animals were considered as a control group.

Relation:

Neuropatologia Polska

Volume:

23

Issue:

4

Start page:

493

End page:

506

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:68835

Language:

pol

Language of abstract:

eng ; rus

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open