Inny tytuł:

Mechanisms determining bacterial biofilm resistance to antimicrobial factors

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Bacterial biofilm resistance is a very serious problem of modern medicine and industry practice. Microorganisms forming biofilm initiate multilevel resistance mechanisms that protect cells against antibacterial substances. This resistance is higher than antibiotics and disinfectants tolerance of planktonic bacteria. Ineffective of antibacterial compounds action on biofilm depends on biofilm structure, slowing down the antibiotics diffusion speed, environmental factors in which biofilm is formed, the presence of capsule of bacteria and the activity of “efflux pumps” proteins. The process of signal molecules formation by bacteria and releasing them to the medium is also very relevant aspect. In this paper, the changes in the molecular level that induces bacterial biofilm resistance against antimicrobial agents are also described.

Czasopismo/Seria/cykl:

Biotechnologia, vol.76, 1 (2007)-.

Tom:

76

Zeszyt:

1

Strona pocz.:

40

Strona końc.:

52

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:87147 ; IChB B-72

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open