Title:

Possible involvement of astroglial expression of cytokines in neuronal degeneration after transient global ischemia in rat brain. (Abstracts from XI Conference of Polish Association of Neuropathologists, Warszawa, 13-15.05.1999)

Creator:

Orzyłowska, O. ; Oderfeld-Nowak, B. ; Kamińska, B. ; Zaremba, Marcin ; Januszewski, Sławomir ; Mossakowski, Mirosław Jan (1929–2001)

Publisher:

Severus Publishing House

Place of publishing:

Warsaw

Date issued/created:

1999

Type of object:

Journal/Article

Subject and Keywords:

Ischemia ; cytokines

Abstract:

Studies from various laboratories have shown that cytokines may play an important role in ischemic brain injury. Particular interest revolves around the role of the two interleukins: interleukin -lbeta (IL-1 beta) and interleukin-6. Although these pleiotropic cytokines have been described as having both pro- and anti-inflammatory properties, IL-lbeta has been mainly postulated as a mediator in the pathogenesis of ischemic damage, while IL-6 appears mostly involved in the neuroprotective action. The balance between the opposing actions of these two cytokines may be an important element in determining the outcome after ischemic insult.

Relation:

Folia Neuropathologica

Volume:

37

Issue:

4

Start page:

303

End page:

303

Resource type:

Text

Detailed Resource Type:

Article : short communication

Format:

pdf

Language:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open