Title:

PRZYPADEK DZIECIĘCEJ POSTACI IDIOTIA AMAUROTICA (TAY-SACHS). OPRACOWANIE NEUROPATOLOGICZNE I HISTOCHEMICZNE

Creator:

Dąmbska, Maria ; Czochańska, Jagna ; Mossakowski, Mirosław Jan (1929–2001)

Publisher:

Państwowy Zakład Wydawnictw Lekarskich

Place of publishing:

Warszawa

Date issued/created:

1962

Subject and Keywords:

idiotia amaurotica (Tay-Sachs)

Abstract:

A case of the infantile form of amaurotic idiocy is presented. The case showed the typical clinical picture and course. Specific ophthalmological lesions were present. Pathologic examination of the brain showed the typical morphology of this form of the disease. The relatively slight damage to the cerebellum was the only pathologic peculiarity of the case. Histochemical examination revealed that the materiał stored in the neuronal cytoplasm was a mixture of lipid compounds. Neuraminic acid—free glycolipid were the principal substances stored, and were not bound with cellular protein. The retinal ganglion cells were filled with similar lipid substances. However, their histo¬chemical properties were similar to those typical for the late infantile form of the disease.

Relation:

Patologia Polska

Volume:

13

Issue:

2

Start page:

159

End page:

171

Resource type:

Text

Detailed Resource Type:

Article : case study

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open