Metadata language
Erzeugung Immunologischen Toleranz in Experimenteller Allergischeer Encephalitis /EAE/
Subtitle: Creator: Contributor:Czarnocki, D. ; Mossakowski, Mirosław ; Rap, Zbigniew ; Weinrauder, Halina
Publisher:Verlag der Wiener Medizinischen Akademie
Date issued/created: Description: Type of object: Subject and Keywords: Abstract:Considering the resemblance of immunological mechanismus between graft-reject-reaction and Experimental Allergic Encephalitie /E.A.E„/ our Ezperiment aimed at inducing a more durable tolerance in E.A.E. In our investigation, the rabbits received 6-Mercaptopurin intravenously, concurrently with the classical immunisation with brain suspension and Freund full adjuvant and for 18 days after. We hoped in this way to eliminate more effectively the specifio immunological clones. After stopping this drug the new sensibilisation of treated rabbits gave a much weaker response both from clinical and histological point of fiew than in control animals. The problems concerning the wider aignificance and the mechanism of the acquired tolerance needs futher conside-ration.
Resource type: Detailed Resource Type: Format: Language: Language of abstract: Rights:Licencja Creative Commons Uznanie autorstwa 4.0
Terms of use:Zasób chroniony prawem autorskim. [CC BY 4.0 Międzynarodowe] Korzystanie dozwolone zgodnie z licencją Creative Commons Uznanie autorstwa 4.0, której pełne postanowienia dostępne są pod adresem: ; -
Digitizing institution:Instytut Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego Polskiej Akademii Nauk
Original in:Biblioteka Instytutu Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego PAN
Projects co-financed by: Access: