Title:

Complexes of PR-10 proteins with plant hormones: crystallographic and biophysical studies

Creator:

Śliwiak, Joanna

Date issued/created:

2017

Description:

Scientific adviser: Prof. Mariusz Jaskólski

Location:

Poznań

Abstract:

This doctoral thesis presents studies of pathogenesis related proteins of class 10 (PR-10). Sofar no specific function has been assign to this group. The PR-10 family consist of small,intracellular biomolecules of acidic character, whose expression is elevated in response to bioticand abiotic stress. The characteristic fold of PR-10 proteins, which consists of seven antiparallelβ strands wrapped around an extended, C-terminal α helix, creates a globular protein with alarge, hydrophobic cavity, which is capable of accommodating small-molecule ligands. Althoughmany constitutively expressed plant proteins exhibit the PR-10 fold, they are not typicallyrelated to pathogenesis. A variety of different ligand classes, including cytokinins, flavonoids andsteroids, have been demonstrated so far (via crystallographic and biophysical methods) tooccupy the PR-10 cavity.

Start page:

1

End page:

131

Resource type:

Text

Detailed Resource Type:

PhD Dissertations

Format:

application/pdf

Language:

eng

Language of abstract:

eng ; pol

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

-

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open