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Fidziańska-Dolot, Anna (1930–2015)
Institutional creator:Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Contributor:Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Place of publishing: Date issued/created: Description:Electron microscopy analysis of the heart biopsy
Subject and Keywords: Abstract:Significant changes in sarcomere pattern were observed. The ultrastructural evaluation revealed also changes in the course of myofibrils and their disorganization, often a total loss of myofibrils was noticed. Quite numerous lipid droplets were visible. The cardiomyocyte nuclei were characterized by abnormal shape, the nuclear envelope was corrugated, forming numerous invaginations, and broken in some parts. Some nucleicontained cellular organelles inside them. Focally, especially in the vicinity of cardiomyocyte nuclei deposits of lipofuscin were seen. A large accumulation of mitochondria was observed in sarcoplasm. Some of them showed ultrastructuralchanges - abnormal arrangement of mitochondrial cristae was visible.
Resource type: Detailed Resource Type: Format: Language: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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