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Boczkowska, Małgorzata ; Guga, Piotr
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:The methods of evaluation of thermodynamic parameters for oligonucleotide order-disordertransitions are presented. These parameters are useful for the prediction of stability of duplexesformed by these oligonucleotides with RNA matrix. The common opinion, that better antisenseproperties can be achieved by the increase of oligonucleotide length is critically evaluated. Theproblem of optimal length of oligonucleotide for antisense purposes is discussed by taking intoaccount the selectivity of hybridization.
Relation:Biotechnologia, vol.27, 4 (1994)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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