Title:

Glyco-centres of Faba bean globulins as a source of epitops

Subtitle:

Glyco-centres of Faba bean globulins as a source of epitops

Creator:

Kostyra, Henryk ; Kostyra, Elżbieta ; Krawczuk, Stanisław ; Jarmołowska, Beata

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2001

Subject and Keywords:

biotechnology

Abstract:

The reaction of non-enzymatic glycation of Faba bean globulins progressedeffectively in weakly basic medium. The cross-linking of globulins was formedfirst of all in the results of Schiffs reaction between amine group of Lys and aldehyde group of glucose. The glycated globulins demonstrated higher immunogenicactivity in comparison with the non-glycated ones. This means that non-enzymatic glycation of Faba bean globulins caused the formation of new epitops inthe pepide chains. The results achieved prove that non-enzymatic glycation ofFaba bean globulins changes their immunogenic properties.

Relation:

Biotechnologia, vol.54, 3 (2001)-.

Volume:

54

Issue:

3

Start page:

202

End page:

207

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-50

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open