Regulatorowe kwasy rybonukleinowe

Żywicki, Marek; Szymański, Maciej; Barciszewska, Mirosława Z.; Barciszewski, Jan

doi:0860-7796

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Regulatorowe kwasy rybonukleinowe Żywicki, MarekSzymański, MaciejBarciszewska, Mirosława Z.Barciszewski, Jan

Object structure

Regulatorowe kwasy rybonukleinowe

Regulatory ribonucleic acids

Żywicki, Marek ; Szymański, Maciej ; Barciszewska, Mirosława Z. ; Barciszewski, Jan

Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN

2003

biotechnologia

In recent years there was a growing number of reports of new non-protein-coding RNAs which are implicated in the regulation of many cellular processes. They differ in many respects from already known housekeeping RNAspecies involved in protein biosynthesis (tRNA, rRNA) and RNA maturation ormodification (RNase P RNA, snRNAs, snoRNAs). Regulatory RNAs (riboregulators)are expressed only in certain cell types, at particular stages of organism development or cell differentiation or in response to biotic and abiotic stimuli. Theirexpression is usually accompanied by the alteration of patterns of the expression of other genes. The mechanisms employed by riboregulators can affecttranscription, pre-mRNA processing and translation. In the post-genomic era,the noncoding regulatory RNAs emerge as key determinants of organismal complexity, providing efficient and highly specific means for integration of variouscellular processes.

Biotechnologia, vol.61, 2 (2003)-.