TY - GEN N2 - Botulinum toxin is a neurotoxin protein produced by the bacterium Clostridium botulinum. It is one of the most poisonous, naturally occurring substances in the world and it is the most toxic protein. Although it is highly toxic, it is used in medicine. Clinical applications of botulinum toxin, which include the treatment of overactive skeletal and smooth muscles, hypersecretory and painful disorders as well as cosmetics applications, have increased exponentially since it was first used clinically to treat strabismus more than two decades ago. This paper describes the structure, mechanism of action and application of botulinum toxin. L1 - http://www.rcin.org.pl/Content/72128/PDF/POZN271_94532_biotechnologia-2009-no2-pisarek.pdf M3 - Text J2 - Clostridium botulinum toxin - a wonderful poison PY - 2009 IS - 2 EP - 133 KW - biotechnology A1 - Mazurkiewicz-Pisarek, Anna A1 - PĹ‚ucienniczak, Andrzej PB - Committee on Biotechnology PAS PB - Institute of Bioorganic Chemistry PAS VL - 85 SP - 123 T1 - Clostridium botulinum toxin - a wonderful poison UR - http://www.rcin.org.pl/dlibra/publication/edition/72128 ER -