TY - GEN N2 - Studies from various laboratories have shown that cytokines may play an important role in ischemic brain injury. Particular interest revolves around the role of the two interleukins: interleukin -lbeta (IL-1 beta) and interleukin-6. Although these pleiotropic cytokines have been described as having both pro- and anti-inflammatory properties, IL-lbeta has been mainly postulated as a mediator in the pathogenesis of ischemic damage, while IL-6 appears mostly involved in the neuroprotective action. The balance between the opposing actions of these two cytokines may be an important element in determining the outcome after ischemic insult. L1 - http://www.rcin.org.pl/Content/71917/PDF/publ_277.pdf M3 - Text PY - 1999 IS - 4 EP - 303 KW - Ischemia KW - cytokines A1 - Orzyłowska, O. A1 - Oderfeld-Nowak, B. A1 - Kamińska, B. A1 - Zaremba, Marcin A1 - Januszewski, Sławomir A1 - Mossakowski, Mirosław Jan (1929–2001) PB - Severus Publishing House VL - 37 CY - Warsaw T1 - Possible involvement of astroglial expression of cytokines in neuronal degeneration after transient global ischemia in rat brain. (Abstracts from XI Conference of Polish Association of Neuropathologists, Warszawa, 13-15.05.1999) SP - 303 UR - http://www.rcin.org.pl/dlibra/publication/edition/71917 ER -