TY - GEN N2 - The effect of transient, global cerebral ischemia on the distribution of endothelin (ET) in blood-brain barrier (BBB) in CAI area of hippocampus long-time after ischemia was estimated using post-embedding immunogold technique. ET-like immunoreactivity as a gold particles was localized in all compartments of the blood-brain barrier e.g. in endothelial cells, in pericytes, in periendothelial space including basement membrane, and in astroglial processes. In control animal the density of labelling in all elements of BBB in CAI area of hippocampus was moderate. ET-like immunoreactivity (ET-like IR) was estimated 1 week - 12 months after ischemia. Intense ET-like IR in all elements of BBB was noted 2 and 6 months after ischemia. A potential pathophysiological role of endothelin in cerebral vasospasm in long-time after ischemia is well documented. L1 - http://www.rcin.org.pl/Content/71897/PDF/publ_268.pdf M3 - Text PY - 1997 IS - 1 EP - 59 KW - ischemia KW - Endothelins KW - immunocytochemistry KW - Blood-brain barrier KW - hippocampus A1 - Gajkowska, Barbara A1 - Mossakowski, Mirosław Jan (1929–2001) PB - Severus Publishing House VL - 35 CY - Warsaw SP - 49 T1 - Endothelin-like immunoreactivity in hippocampus following transient global ischemia. II. The blood-brain interphase UR - http://www.rcin.org.pl/dlibra/publication/edition/71897 ER -