TY - GEN N2 - Cultured chondrocytes seeded on appropriate scaffold can be used in treatment of vesico-uretheral-reflux. Aims; influence of alginate scaffold on extracellular matrix production by rats chondrocytes. Observation of alginate degradation in rat bladder. Dedifferentiated chondrocytes were seeded onto alginate fibers and alginate gel beads and stained with alcian blue. Alginate was injected in bladder wall of 10 rats with following histological examination (H-f E and alcian blue). Chondrocytes became round on alginate fibers and glycosaminoglicane positive in alginate beads. Volume of the implanted alginate decreased after 8'*’ week. Alginate gel allows chondrocytes to reexpress phenotype. L1 - http://www.rcin.org.pl/Content/119342/PDF/POZN271_148631_biotechnologia-2004-no3-drewa.pdf M3 - Text J2 - Preliminary study on alginate scaffold application for chondrocytes transplantation into the rat bladder wall PY - 2004 IS - 3 EP - 224 KW - biotechnology A1 - Drewa, Tomasz A1 - Wolski, Zbigniew A1 - Gałązka, Przemysław A1 - Sir, Jan A1 - Woźniak, Alina A1 - Czaplewski, Artur PB - Committee on Biotechnology PAS PB - Institute of Bioorganic Chemistry PAS VL - 66 SP - 213 T1 - Preliminary study on alginate scaffold application for chondrocytes transplantation into the rat bladder wall UR - http://www.rcin.org.pl/dlibra/publication/edition/119342 ER -