@misc{Kapuściński_Andrzej_(1937–2018)_Quantitative_1973,
 author={Kapuściński, Andrzej (1937–2018) and Mossakowski, Mirosław Jan (1929–2001)},
 copyright={Creative Commons Attribution BY 4.0 license},
 howpublished={online},
 year={1973},
 language={eng},
 abstract={Adult Albino rats (290) were investigated under aether anaesthesia in the following groups: 1. control 2. unilateral ligation of the common carotid artery 3. bilateral ligation of these arteries 4. unilateral ligation of the c. c. artery and exposure to anoxia or hypoxia (4 % 02). I—HSA, vTc04, Na I, Na Br, I—4—I—antipyrine and Se — selenomethionine were injeoted i. v. in all of these groups. Parallel optic microscopic and histochemical (glycogen) studies vere performed. The activity of each hemisphere and of a blood sample were measured in a well — type scintillation oounter mainly between 10 min and 5 h and in some eases up to 96 h after induotion of patho-logy. The results were expressed for each hemisphere as: ifD/g corrected for body weight, ratio of brain/blood specific activities and M D in whole blood. In one group of animals, whole blood volume and the brain blood volume were determined. Compara-tive transport into normal cerebral tissue was as foliows: |131I—4—I—antipyrina 75Se—selenomethionine Na82Br Na131J 9SmTcO ,13,J —HSA. There were no statistical differences as compared with the control group in the transport of these compounds into brain tissue after unilateral and bilateral ligation of the c. c. artery. Anoxia (5 min) and hypoxia up to 3 h eaused no changes in transport of these compounds. In the ischaemic—hypoxic group penetration of these compounds into the damaged hemisphere was much higher in the majority of cases. The authors suggest that the ischaemic factor in this model is mainly responsible for the development of oedema with progressive damage of brain},
 title={Quantitative evaluation of transport of some labelled compounds into rat cerebral tissue under normal conditions and during ischaemia and hypoxia of brain},
 type={Text},
 URL={http://www.rcin.org.pl/Content/69670/PDF/Quantitative%20evaluation.pdf},
 keywords={Brain ischemia, Brain hypoxia},
}