@misc{Przybecki_Z._Molekularne_1992, author={Przybecki, Z. and Malepszy, S.}, volume={18}, number={3}, copyright={Creative Commons Attribution BY-SA 4.0 license}, journal={Biotechnologia, vol.18, 3 (1992)-.}, howpublished={online}, year={1992}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={pol}, abstract={The variability, to be appeared as an in vitro culture result has been called somaclonal variation, andoccured to be serious problem for wide sense biotechnology of plants. The variability has been obtained,can be both, geneticai or epigenetical nature. The wide changes induced by in vitro culture factors havebeen causes of that fenomenon, mainly during “unorganized" growth faze. The advances in molecular investigations of somaclonal variation, to be obtained for the last few years, allowed to find some processescould be responsible for somaclonal variation appearing. At present, the main fenomenons leading to appearance of the somaclonal variation have been thought: changes of methylation pattern, amplificationand deamplification of DNA, nucleotide pull imbalance, late replication of chromatin, transpozons, and different type of recombinations.}, title={Molekularne podstawy zmienności somaklomalnej u roślin}, type={Text}, URL={http://www.rcin.org.pl/Content/163079/PDF/POZN271_197020_biotechnologia-1992-no3-przybecki.pdf}, keywords={biotechnology}, }