@misc{Malewski_Tadeusz_Distribution_2004, author={Malewski, Tadeusz and Glazko, Galina and Sazanov, Alexei}, volume={66}, number={3}, copyright={Creative Commons Attribution BY-SA 4.0 license}, journal={Biotechnologia, vol.66, 3 (2004)-.}, howpublished={online}, year={2004}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={pol}, abstract={Precise analysis of gene transcription regulation requires accurate estimation of gene regulatory elements. Transcription factors (TF) binding sites are distributed unevenly along gene 5'-upstream sequences. The analysis of gene 5'-upstream sequences showed the presence of high-density regions of transcription factor binding sites (HDR). The first FIDR adjacent to the transcription start point corresponds to a minimal promoter, and the 5’-end of l-HDR corresponds to the 5’-end of minimal promoter.}, type={Text}, title={Distribution of transcription factor binding sites along 5’-upstream sequences of genes: estimation of minimal promoters and upstream regulatory regions}, URL={http://www.rcin.org.pl/Content/119509/PDF/POZN271_148817_biotechnologia-2004-no3-malewski.pdf}, keywords={biotechnology}, }