@misc{Koziołkiewicz_Maria_Stabilność_1994,
 author={Koziołkiewicz, Maria},
 volume={27},
 number={4},
 copyright={Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0},
 journal={Biotechnologia, vol.27, 4 (1994)-.},
 howpublished={online},
 year={1994},
 publisher={Komitet Biotechnologii PAN},
 publisher={Instytut Chemii Bioorganicznej PAN},
 language={pol},
 abstract={Nucleolytic enzymes (5 - and 3'-nucleases, exo- and endonucleases) can degrade short unmodified oligonucleotides applied as potential antisense agents. Better stability of oligonucleotidesagainst nucleolytic enzymes can be achieved by chemical modification of intemucleotide bonds.Stability of the phosphorothioate, phosphorodithioate and methylphosphonate analogues of oligonucleotides against nuclease PI, 3'-exonuclease, snake venom phosphodiesterase and other nucleases is discussed.},
 title={Stabilność oligonukleotydów antysensowych— możliwości ich degradacji enzymatycznej},
 type={Tekst},
 URL={http://www.rcin.org.pl/Content/148130/PDF/POZN271_183639_biotechnologia-1994-no4-koziolkiewicz.pdf},
 keywords={biotechnologia},
}